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  • ِFormation of New C-C for Aldhydes and ketones

    ِFormation of New C-C for Aldhydes and ketones

    To understand this simple reaction try to convert Acetone into t-butyl alcohol. Organometalic nucleophile usage Examples of organometallic reagent: R-Li , Grignard reagent. As you see you can add what ever group you need R to the carbonyl by adding it to lithium which make it suitable nucleophile (HOMO) to attack carbonyl group (LUMO). Mechanism:…

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